Ed Killifer is a fictional DEA agent and colleague of Felix Leiter, who turns traitor when he accepts a $2 million bribe to free drug baron Franz Sanchez from U.S. custody. He appears in the 1989 James Bond film Licence to Kill and was portrayed by Everett McGill.
Killifer is first introduced to Bond at the wedding of Felix and Della Leiter. He congratulates Bond on his capture of drug lord Franz Sanchez. He is later seen in a detention center, intimidating Sanchez that he has a one-way ticket to Quantico. Killifer also says this is not Sanchez's native country where law enforcement, judges and politicians can be bought, not even for $1 million. Sanchez then asks "$2 million?"
Killifer is then seen in a police van carrying Sanchez, sitting in the passenger seat. Without warning, Killifer grabs a rifle and butt-strokes the driver, causing him to lose control of the vehicle and plunge off Seven Mile Bridge into the waters of Key West, causing the driver and all DEA agents protecting Sanchez to drown. Sanchez and Killifer then escape in a Shark Hunter two-man submersible, courtesy of Sanchez's associate, Milton Krest.
After Killifer frees Sanchez, he enters the murky world of drug lord justice. Sanchez's underling Dario is urging his boss to just get home and forget about some American they hardly know, but Sanchez says Killifer held up his end of the deal by freeing him; so too is he obligated to present the promised cash to Killifer. He collects his payment, but then must endure watching Felix Leiter lowered into a shark tank to be maimed by a Great White Shark, which does not seem to overly bother him and he brushes off Leiter's tirades, saying big bucks do not come every day. Waiting to be picked up at Krest's Ocean Exotica warehouse, Killifer hears gunshots outside the office and finds that James Bond has killed two guards. Holding 007 at gunpoint with a revolver, he opens the same trap door which was used in the dunking of Leiter.
Before he can shoot Bond or usher him into the tank, he is knocked off balance by Leiter's fisherman friend Sharkey, who emerges from another trap door directly below him. Bond seizes the opportunity and punches him into the shark tank. As he dangles from a rope over the water, Killifer offers to split the bribe money with Bond if he saves him. The spy refuses, telling him "You earned it. You keep it, old buddy." and coldly slings the case of money at him, knocking him into the shark tank where he is killed by the same shark who mauled the man he sold out for a fast buck.