The MP5K is one of the submachine guns that are used in 007: Everything or Nothing. It has a small magazine but is quite strong. It can stop a person with one shot, and bring him down with the next.

In 007: Nightfire the MP5K appears in the game as the "Deutsche M9K", and has a 21-round magazine (despite the real MP5K having only 15 or 30-round box magazines) and a removable silencer.

It is also used in GoldenEye (video game) as the D5K Deutsche and D5K Silenced.

Bond uses the M5PK in Tomorrow Never Dies during the final gunfight in the film.