The Museum Guide is one of the many henchwoman working for Hugo Drax's evil plan. She is a museum guide at the museum Bond goes to and reacts nervously once she sees him. In her duties as a docent, she told a tour group about an expensive porcelain bowl and then momentarily activated an invisible radar alarm by attempting to touch the bowl, showing what happens to those who think the bowl is unguarded. The bowl was later destroyed by Bond is his fight against Chang.
She is also present when the girls attempt to kill Bond with an anaconda. Her final fate is unknown, though it is assumed that she is killed in some manner during the final battle.