Mr. Osato is the head of Osato Chemicals and Engineering and also a member of SPECTRE in the 1967 James Bond film You Only Live Twice. He is a SPECTRE henchman to Ernst Stavro Blofeld and is portrayed by Teru Shimada.
When Bond follows an assassin of his Japanese contact Dikko Henderson, he goes to Osato's company and finds a safe that tells him a few things. Bond then meets Mr. Osato (Bond posing as Mr. Fisher, the new managing director of Empire Chemicals) and Helga Brandt, his henchwoman and SPECTRE No.11. Osato then orders his men to kill Bond, who escapes thanks to Aki. Osato then captures Bond, and leaves him with Helga, for her to kill. Bond manages to survive again.
Ernst Stavro Blofeld then summons Osato and Brandt to his quarters for an urgent report, and reprimands them for failing to kill Bond. Blofeld gives Osato and Brandt the strictest order to kill Bond; however, Blofeld decides to kill Helga Brandt for her failure and Osato is left on his own. Osato then attempts to kill Bond by using a fake ninja who has a knife but Bond outsmarts him. The other way is by dropping poison into his mouth while he is asleep, which because he turned over, killed Aki instead. Both these attempts were carried out by his henchmen, and Osato is at the end scene. Bond is captured by Osato and Blofeld, after his attempt to infiltrate the SPECTRE Volcano. Blofeld takes his gun and points it at Bond, saying "This is the price of failure, Mr. Bond," but then he turns the gun and shoots Osato instead.
- Despite working for SPECTRE he doesn't seem to be an actual member, as he is always referred to by Blofeld as "Osato" rather than a number as all other members are.